Beyond Prediction. True Evolution.
Conventional Biologics
- Single-target, single-mechanism therapeutics
- Complex manufacturing & cold chain requirements
- Limited sequence space exploration
- Prediction-based design with high failure rates
- Fixed pharmacology locked to single modality
Fabricagen Evolved Therapeutics
- Multi-target peptide agonists & antagonists
- Engineered conjugates with optimized stability
- Evolutionary search across vast design spaces
- Directed evolution with real-time quality gates
- Modular PD on a fixed PK scaffold
Engineering the Next Generation
Our platform combines AI-driven evolution with precision bioconjugation to create peptide therapeutics with unprecedented modularity.
Peptide Evolution Engine
AI-guided directed evolution explores billions of peptide variants, selecting for binding, stability, and selectivity in parallel.
Modular Conjugation
Precision bioconjugation links evolved peptides to engineered scaffolds. Mix and match pharmacodynamics on a proven PK platform.
Multi-Agonist Architecture
Single molecules targeting 2-3 pathways simultaneously. Dual and tri-peptide conjugates for complex disease biology.
Fixed PK Scaffolds
Validated carrier platforms with known half-life profiles. Tune efficacy without reformulating pharmacokinetics.
Developability-First
Every candidate assessed for aggregation, stability, and manufacturability. No late-stage surprises.
Continuous Optimization
Iterative evolution cycles improve candidates based on assay feedback. Biology guides the algorithm.
Evolution at Scale
Our platform explores sequence space that traditional methods can't reach.